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As patients with liver metastasis are more likely to develop cholestasis and are refractory to immunotherapy, such as anti-PD treatment (89), the addition of UDCA to therapeutics may be beneficial

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Although methylcobalamin and vitamin B12 are terms used interchangeably, vitamin B12 is also available as hydroxocobalamin, a less commonly prescribed drug product (see Hydroxocobalamin monograph), and methylcobalamin

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